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US-Iran Talks Fail After Historic 21-Hour Session as Hormuz and Nuclear Disputes Leave Ceasefire Fragile

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US-Iran talks

ISLAMABAD, Pakistan — The United States and Iran ended a 21-hour round of face-to-face negotiations without an agreement early Sunday, leaving a two-week ceasefire shaky as the sides clashed over Tehran’s nuclear program, control of the Strait of Hormuz and the terms of a broader regional calm, April 12, 2026.

The breakdown exposed how far apart the two governments remain. Washington says any durable arrangement must include an explicit Iranian pledge not to seek a nuclear weapon and restrictions that would keep Tehran from moving quickly toward one. Iran, meanwhile, has tied any broader settlement to sanctions relief, access to frozen funds, shipping rights in Hormuz and an end to fighting involving its regional partners.

Multiple accounts, including Reuters reporting from Islamabad and AP’s account of the closing session, described the marathon meeting as the first direct U.S.-Iran encounter in more than a decade and the highest-level face-to-face contact since the 1979 Islamic Revolution.

Why the US-Iran talks broke down

At the center was a familiar dispute with new wartime consequences: the United States wants Iran to curb or dismantle key parts of its nuclear activity, while Iran insists its leverage in Hormuz and the wider region must translate into political and economic gains. The problem was never purely bilateral. Israel’s continuing campaign against Hezbollah in Lebanon remained one of the issues making a wider ceasefire harder to separate from the Washington-Tehran file.

The truce itself remains narrow and unstable. Reuters’ ceasefire explainer noted that the two sides entered negotiations with sharply different agendas, while shipping through Hormuz was only partially resuming and energy markets remained sensitive to any sign the waterway could tighten again.

That shipping risk matters far beyond the Gulf. Roughly a fifth of globally traded oil normally passes through the strait, and even limited disruption can ripple quickly into freight, insurance and fuel costs. The fact that a small number of vessels moved during the truce did little to settle the deeper fight over who controls passage and on what terms.

The nuclear file is just as unsettled. In its latest IAEA safeguards report, the U.N. watchdog said its last estimate put Iran’s stockpile at 440.9 kilograms of uranium enriched to 60% and warned that disrupted inspections increase the risk that the agency cannot assure declared inventories have not been diverted. That technical backdrop helps explain why Washington framed the talks around explicit nuclear limits rather than a looser political understanding.

How earlier US-Iran talks led here

The collapse in Islamabad did not come out of nowhere. In 2015, Iran and six world powers reached the nuclear deal known as the JCPOA, a breakthrough that capped more than a decade of negotiations. In 2018, Washington withdrew from that agreement and restored sanctions, reopening the path to the long-running standoff that followed. By April 2025, Oman-mediated contacts between the two sides were again being described as positive and constructive, suggesting there was still room for diplomacy even after the old framework had broken down.

That history is why the failed session in Pakistan matters. The talks were not just an emergency attempt to steady a two-week ceasefire; they were also a test of whether the two governments could move from wartime bargaining back toward structured negotiation. For now, that bridge has not been built.

What comes next is narrower than either side wanted. Pakistan says it wants to keep the channel open, but unless Washington and Tehran reduce their demands, the ceasefire will remain vulnerable to the next missile launch, shipping incident or Israeli strike in Lebanon. The session may have been historic for its length and symbolism, but without movement on Hormuz or the nuclear issue, history alone was not enough to produce a deal.

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